Above all else, the mentat must be a generalist, not a specialist. It is wise to have decisions of great moment monitored by generalists. Experts and specialists lead you quickly into chaos. They are a source of useless nit-picking, the ferocious quibble over a comma. The mentat-generalist, on the other hand, should bring to decision-making a healthy common sense. He must not cut himself off from the broad sweep of what is happening in this universe. He must remain capable of saying: "There's no real mystery about this at the moment. This is what we want now. It may prove wrong later, but we'll correct that when we come to it." The mentat-generalist must understand that anything which we can identify as our universe is merely part of larger phenomena. But the expert looks backward; he looks into the narrow standards of his own specialty. The generalist looks outward; he looks for living principles, knowing full well that such principles change, that they develop. It is to the characteristics of change itself that the mentat-generalist must look. There can be no permanent catalogue of such change, no handbook or manual. You must look at it with as few preconceptions as possible, asking yourself: "Now what is this thing doing?The Mentat Handbook - Dune

Many things we do naturally become difficult only when we try to make them intellectual subjects. It is possible to know so much about a subject that you become ignorant.
Mentat Text Two (decto) - Dune

Truth suffers from too much analysis.
Ancient Fremen Saying - Dune

"Do not accept anything simply because it has been said by your teacher, or because it has been written in your sacred book, or because it has been believed by many, or because it has been handed down by your ancestors. Accept and live only according to what will enable you to see truth face to face."
- Buddha, as quoted in *Peace Is Every Step: The Path of Mindfulness in Everyday Life* by Thich Nhat Hanh